Mission
Our mission is to make significant contributions to the understanding of legacies of stress so that they can be halted.
We aim to do so by
Mission
Our mission is to make significant contributions to the understanding of legacies of stress so that they can be halted.
We aim to do so by
- being creative and collaborative in our conceptual and technical approaches,
- conducting and communicating our research with integrity and clarity, and
- providing a collegial and caring training environment for the next generation of neuroscientists.
Vision
Our research seeks to understand how mammalian neurobiology, physiology and reproductive biology is impacted by stress or trauma, and how parental legacies of stress or trauma influence offspring.
Armed with this understanding, we aim to propose and test strategies that could halt legacies of stress or trauma from perpetuating across generations.
Approach
We use molecular, cellular, genetic, epigenetic, physiological, and behavioral approaches to investigate how the biology of an organism and its responsiveness to stress or trauma is influenced by micro- (genome, epigenome and hormones), and macro-environments (ancestral, in utero and post-natal experiences).
Informing these approaches are our past, and current experiences with a variety of model systems (rats, lizards, fruit-flies, mice) and scientific disciplines (stress neurobiology, endocrinology, neurogenetics, epigenetics, physiology, innate & learned behavioral repertoires).
While most of our studies use mice, we are also investigating the biological basis of behavioral states and neuropsychiatric disorders by pursuing collaborations that involve the study of non-human primates, and humans.
